Endocrine Abstracts

Introduction: Graves’ hyperthyroidism is an autoimmune disease sustained by autoantibodies binding to and activating the TSH receptor located on the thyroid follicular cell. The objective of study was to determine the presence of anti-receptor TSH antibodies for the diagnosis of Grave’s diseases and the following up after surgery, iodine and treatment with antithyroid drug.Results: In years 2006–2010 in our clinic in 265 patients for thyro...

Background: Diabetes mellitus (DM) is a common metabolic disorder and is associated with development of chronic macrovascular complications leading to significant morbidity and mortality. The aim of the study was to evaluate the prevalence and clinical profile of macrovascular complications in diabetic patients in Korca, Albania.Material and methods: A total of 456 cases with type 2 DM attending Department of Endocrine (outpatient/inpatient), from Januar...

Background: Iodine Deficiency (ID) represent a significant public health problem globally, particularly among pregnant women.Aim: To estimate the prevalence and predictors of ID among pregnant women residing in Durres AlbaniaMethods: A survey cross-sectional study conducted on 162 pregnant women, from May to June 2021. Demographic information, iodized salt usage, and other clinical information were collected using a questionnaire c...

Introduction: Co-occurrence of differentiated thyroid carcinoma (DTC) and chronic autoimmune thyroiditis (HT) is a debatable subject in many studies. It’s noted that patients with HT have less aggressive tumors and a better prognosis, possibly related to the immune response against tumoral cells.Aim: To evaluate demographic, clinical, laboratorial, histopathological parameters in patients with HT and DTC, compared to the patients without HT, focusin...

Background: Fahr’s Syndrome, also known as striopallidodentate calcinosis is a rare form of neurological disorder characterized by abnormal calcified deposits in basal ganglia, cerebellar and cerebral cortex. Its prevalence goes from 2 to 12.5%. Etiology of this disorder is very wide and involves endocrinopathy, mitochondrial myopathies dermatological abnormalities, infectious disease or may be idiopathic. We present a case of a patient with diffuse brain calcifications d...

Background: Nephrocalcinosis is characterized by the deposition of calcium products in kidney parenchyma and tubules. It may cause acute or chronic kidney injury or be incidentally detected radiographically in a patient with normal kidney function. Most patients with nephrocalcinosis do not progress to end-stage kidney disease, but with certain underlying conditions, may be associated with progressive kidney dysfunction.Methods: The patient was diagnosed...

Introduction: Occult papillary carcinomas are small thyroid carcinomas (<1 cm) diagnosed after an initial manifestation of lymph nodes or distant metastasis. We report two cases of patients with this pattern of clinical presentation.Case description: The first case is a 21-year-old woman, with a one-year history of a growing cervical cyst. Fine needle aspiration of the cyst showed metastasis from papillary thyroid cancer. She had no previous history ...

Aim: To see the difference between salivary cortisol values and correlation with the work stress.Methods: The salivary and serum cortisol values were analysed in two groups of nurses, six nurses in the Emergency Department and six nurses in the Pathology Department at our hospital, three females and three males for each group. The samples were taken before beginning the work and after finishing the work. The cases respected all the rules for salivary tes...

Introduction: APS-2 is the most common autoimmune polyendocrine syndrome. It is characterized by the presence of various endocrine-related diseases, such as autoimmune thyroid disease, type 1 diabetes mellitus, Addison’s disease, primary hypogonadism, and, in rarer cases, hypoparathyroidism or hypopituitarism.Case report: Our patient is a 38-year-old female with a medical history of type 1 diabetes mellitus (DMT1) for 13 years, Hashimoto’s thyr...

Background: We present a rare case of a 64-year-old patient diagnosed with longstanding untreated Graves’ disease and co-occurrence of metastatic thyroid cancer. Very few cases are reported in literature where the thyrotoxicosis in due to the distant metastasis and optimal treatment remains challenging.Case Presentation: The patient came to the endocrine unit for thyrotoxicosis treatment. He was diagnosed with Graves’ disease and following trea...